Proctored Pharmacology ATI

Correct Answer: C

Rationale: Filgrastim is known to cause bone pain as a common side effect. Therefore, it is crucial for clients to report any bone pain to their healthcare provider to monitor for potential complications or the need for further management.

Correct Answer: A

Rationale: When administering Spironolactone, it is essential to monitor the client's serum potassium levels because Spironolactone is a potassium-sparing diuretic. Monitoring potassium levels helps to detect hyperkalemia, a potential adverse effect of the medication.

Correct Answer: A

Rationale: Acetaminophen is known to lose its effectiveness in controlling pain beyond a dosage of 1,000 mg. It is important to adhere to recommended dosages to ensure optimal pain relief and avoid potential adverse effects associated with higher doses.

Correct Answer: B

Rationale: Nevirapine should be taken with food to improve gastrointestinal tolerance and prevent nausea. While absorption is not significantly affected by food, taking it with meals can help reduce adverse gastrointestinal effects.

Correct Answer: C

Rationale: Propranolol undergoes extensive first-pass metabolism in the liver. When administered orally, propranolol is extensively metabolized by the liver before reaching systemic circulation, leading to reduced bioavailability. This process is known as first-pass hepatic metabolism, which significantly affects the drug's effectiveness and necessitates higher oral doses compared to other routes of administration.