Proctored Pharmacology ATI

Correct Answer: B

Rationale: Grapefruit juice can inhibit the metabolism of amlodipine, a calcium channel blocker, leading to increased drug levels in the blood. This can result in potentiated side effects and potential toxicity. Therefore, it is important for the client to avoid grapefruit juice while taking amlodipine.

Correct Answer: C

Rationale: Ataxia is a sign of CNS toxicity, which can be a severe adverse effect of Metronidazole.

Correct Answer: A

Rationale: The therapeutic effect of lisinopril, an ACE inhibitor, is indicated by a decrease in blood pressure. Lisinopril works by relaxing blood vessels, leading to a reduction in blood pressure. Monitoring and achieving a decrease in blood pressure is a key outcome when managing hypertension with lisinopril.

Correct Answer: D

Rationale: The expected outcome of Valproate therapy is a decrease in seizure activity. Valproate is commonly used in the treatment of epilepsy to help control and reduce seizure frequency.

Correct Answer: D

Rationale: Leucovorin, a folic acid derivative and an antagonist to Methotrexate, is given within 12 hours of high doses of Methotrexate to protect healthy cells from the toxic effects of Methotrexate. It helps to reduce the bone marrow suppression and gastrointestinal side effects caused by Methotrexate, supporting the client's overall well-being during chemotherapy treatment.