Proctored Pharmacology ATI

Correct Answer: D

Rationale: Leucovorin, a folic acid derivative and an antagonist to Methotrexate, is given within 12 hours of high doses of Methotrexate to protect healthy cells from the toxic effects of Methotrexate. It helps to reduce the bone marrow suppression and gastrointestinal side effects caused by Methotrexate, supporting the client's overall well-being during chemotherapy treatment.

Correct Answer: B

Rationale: Smoking can interfere with the effectiveness of ranitidine and worsen ulcer symptoms. Clients should avoid smoking while taking this medication to ensure optimal therapeutic outcomes.

Correct Answer: C

Rationale: Prednisone is best taken in the morning to reduce the risk of insomnia, a common side effect of corticosteroids. Instructing the client to take the medication in the morning aligns with the goal of minimizing the impact of insomnia, which can disrupt sleep patterns and affect overall well-being.

Correct Answer: B

Rationale: Grapefruit juice can inhibit the metabolism of amlodipine, a calcium channel blocker, leading to increased drug levels in the blood. This can result in potentiated side effects and potential toxicity. Therefore, it is important for the client to avoid grapefruit juice while taking amlodipine.

Correct Answer: A

Rationale: A common side effect of Albuterol is paradoxical bronchospasm, a condition where the airways become more constricted instead of relaxing, which can be a serious adverse reaction to the medication.