Proctored Pharmacology ATI

Correct Answer: B

Rationale: The client stating that they have been taking an antacid to help with indigestion while on naproxen requires further discussion as it can indicate gastrointestinal distress or potential interactions between the medications. Antacids may affect the absorption of naproxen or lead to other complications, so it is important for the nurse to address this statement with the client.

Correct Answer: B

Rationale: Grapefruit juice affects carbamazepine metabolism and should be avoided. It can lead to increased levels of the medication, potentially causing toxicity. Monitoring carbamazepine blood levels and the complete blood count (CBC) is essential to ensure the medication's efficacy and safety. Carbamazepine can cause serious adverse effects like Stevens-Johnson syndrome, which can be life-threatening. Therefore, the client should promptly report any rash to the healthcare provider. Additionally, the client should be educated about potential central nervous system (CNS) side effects such as drowsiness or dizziness, and advised to avoid activities requiring alertness until these effects diminish.

Correct Answer: D

Rationale: Leucovorin, a folic acid derivative and an antagonist to Methotrexate, is given within 12 hours of high doses of Methotrexate to protect healthy cells from the toxic effects of Methotrexate. It helps to reduce the bone marrow suppression and gastrointestinal side effects caused by Methotrexate, supporting the client's overall well-being during chemotherapy treatment.

Correct Answer: A

Rationale: The therapeutic effect of lisinopril, an ACE inhibitor, is indicated by a decrease in blood pressure. Lisinopril works by relaxing blood vessels, leading to a reduction in blood pressure. Monitoring and achieving a decrease in blood pressure is a key outcome when managing hypertension with lisinopril.

Correct Answer: A

Rationale: Protamine sulfate is the antidote for Heparin. Heparin is an anticoagulant used to prevent blood clotting. Protamine sulfate works by binding to heparin, neutralizing its anticoagulant effects. Vitamin K is not the antidote for Heparin; it is used to reverse the effects of warfarin, another type of anticoagulant. Naloxone is an opioid antagonist used to reverse the effects of opioids, and Toradol is a nonsteroidal anti-inflammatory drug (NSAID) used for pain relief.