Microbiology Chapter 1 Test Bank

Correct Answer: A

Rationale: The Burri-Gins staining technique is used to identify capsule formation in bacteria. Capsules are protective layers around bacteria that can be visualized using this staining method. Capsules are important virulence factors for pathogens like Yersinia pestis, the causative agent of plague. This technique helps in differentiating encapsulated bacteria from non-encapsulated ones. Spore formation (B), acid resistance (C), and alkali resistance (D) are not properties that can be identified using the Burri-Gins technique, making them incorrect choices.

Correct Answer: A

Rationale: The correct answer is A: Metronidazole. Amebic dysentery is caused by the parasite Entamoeba histolytica, not a bacterium, hence antibiotics like Chloramphenicol or Phthalazole are ineffective. Metronidazole is the drug of choice for treating amebic dysentery due to its efficacy against anaerobic organisms like Entamoeba histolytica. Furasolidone is used for treating bacterial infections, not parasitic ones like amebiasis. The patient's symptoms of diarrhea, stomach aches, and a recent history of drinking water from a potentially contaminated source in the forest are indicative of a parasitic infection, supporting the choice of Metronidazole for treatment.

Correct Answer: B

Rationale: The correct answer is B: Aminoglycosides. Aminoglycosides are antibiotics that act by binding to the 30S ribosomal subunit, disrupting protein synthesis in bacteria. This interaction affects the ribosomes directly, leading to inhibition of bacterial protein production. Penicillins (A) work by inhibiting cell wall synthesis, Sulfonamides (C) target folic acid synthesis, and Quinolones (D) inhibit DNA gyrase. These mechanisms do not directly affect the ribosomes, making them incorrect choices in this context.

Correct Answer: A

Rationale: Step-by-step rationale: 1. Mycobacterium tuberculosis is the causative agent of tuberculosis. 2. Mycobacterium tuberculosis is a slow-growing, acid-fast bacterium. 3. It primarily infects the lungs and can spread to other parts of the body. 4. Bacillus anthracis causes anthrax, Clostridium tetani causes tetanus, and Treponema pallidum causes syphilis. 5. Therefore, choice A, Mycobacterium tuberculosis, is the correct answer for the bacteria responsible for tuberculosis.

Correct Answer: D

Rationale: The correct answer is D: Viscerotropic Leishmania. The presence of crescent-shaped bodies with pointed tips, blue cytoplasm, and red nuclei is characteristic of Leishmania species. Viscerotropic Leishmania causes visceral leishmaniasis, also known as kala-azar, which affects the internal organs. Toxoplasma typically presents as tachyzoites, not crescent-shaped bodies. Plasmodium malariae is a malaria parasite with different morphology. Dermatotropic Leishmania causes cutaneous leishmaniasis, not the visceral form indicated by the morphology described in the question.