Medical Microbiology Test Bank

Correct Answer: A

Rationale: The correct answer is A: Rifampicin. Rifampicin can cause red-orange discoloration of bodily fluids like urine due to its metabolism. This phenomenon is harmless but alarming to patients. Isoniazid (B) can cause peripheral neuropathy, Pyrazinamide (C) can cause hyperuricemia, and Ethambutol (D) can cause optic neuropathy.

Correct Answer: B

Rationale: The correct answer is B: Malaria. Fever developing 2 weeks post-blood transfusion is characteristic of malaria due to the incubation period of the parasite. Trypanosomiasis presents earlier, amebiasis usually causes GI symptoms, and toxoplasmosis typically manifests with flu-like symptoms. Malaria is the most likely cause based on the timing and clinical presentation.

Correct Answer: D

Rationale: The correct answer is D. Botulism typically presents with symptoms such as dry mouth, difficulty swallowing, blurred vision, diplopia, and descending flaccid paralysis. Chills, fever, and loss of consciousness are not typical of botulism. Botulism is caused by a neurotoxin produced by Clostridium botulinum bacteria, which affects the nervous system leading to muscle weakness and paralysis, not fever or altered consciousness. Therefore, choice D is the correct answer.

Correct Answer: D

Rationale: The correct answer is D: Protoplast. Lipopolysaccharides of Gram-negative bacteria consist of three main components: O-specific polysaccharide chain, R-specific polysaccharide chain, and Lipid A. Protoplast is not a component of lipopolysaccharides. O-specific polysaccharide chain is responsible for serotype specificity, R-specific polysaccharide chain varies among strains, and Lipid A is the endotoxin component. Protoplast refers to a bacterial cell devoid of a cell wall, which is not a component of lipopolysaccharides.

Correct Answer: A

Rationale: The correct answer is A: Trichomonas vaginalis. Trichomonas vaginalis is a sexually transmitted protozoan that causes trichomoniasis. The pear-shaped flagellated protozoa with an undulating membrane described in the question match the morphology of Trichomonas vaginalis. It is typically found in vaginal discharge of infected individuals. Giardia lamblia (B) is a different protozoan that causes giardiasis and has a distinct morphology of a teardrop shape with flagella. Trypanosoma brucei (C) causes African sleeping sickness and Leishmania donovani (D) causes visceral leishmaniasis, both of which have different morphologies and clinical presentations compared to Trichomonas vaginalis.