Microbiology Chapter 1 Test Bank

Correct Answer: B

Rationale: The correct answer is B: Tuberculosis and mycobacterioses. Mycobacterium tuberculosis, the causative agent of tuberculosis, and other mycobacteria can survive in the soil for extended periods. Here's the rationale: 1. Mycobacteria have a waxy cell wall that provides resistance to harsh environmental conditions. 2. The slow growth rate of mycobacteria allows them to persist in the soil for long periods. 3. Tuberculosis and mycobacterioses are known to be transmitted through environmental exposure, including soil. 4. Colibacillosis and cholera (Choice C) are caused by enteric bacteria that do not survive well in soil. 5. Leptospirosis and plague (Choice D) are bacterial diseases transmitted through animal hosts and are not known to be soil-borne.

Correct Answer: A

Rationale: Rationale: 1. Listeria monocytogenes is a Gram-positive bacterium known for causing foodborne illnesses. 2. Gram-negative bacteria have a different cell wall structure than Gram-positive bacteria, making choice A correct. 3. Choice B is incorrect as Listeria monocytogenes is not encapsulated or sporulating. 4. Choice C is incorrect as Listeria monocytogenes does have a cell wall. 5. Choice D is incorrect as Listeria monocytogenes is indeed a Gram-positive coccobacilli.

Correct Answer: D

Rationale: The correct answer is D: Granulomatosis. The appearance of a 10 mm papule 48 hours after the Mantoux test indicates a delayed-type hypersensitivity reaction, which is characteristic of granulomatosis. This type of reaction involves activation of macrophages and T cells, leading to the formation of granulomas. Granulomas are organized collections of immune cells that wall off the antigen, in this case, the tuberculin antigen. A, B, and C are incorrect: A: Cellular cytotoxicity involves the destruction of target cells by immune cells such as cytotoxic T cells or natural killer cells. This mechanism is not associated with the delayed-type hypersensitivity reaction seen in granulomatosis. B: Anaphylaxis is a rapid and severe allergic reaction involving IgE-mediated release of histamine and other inflammatory mediators. This is not the mechanism underlying the delayed-type hypersensitivity reaction in the Mantoux test. C: Antibody-dependent cytotoxic

Correct Answer: C

Rationale: Rationale: 1. Candida is a fungus commonly isolated from clinical specimens. 2. Sabouraud agar is the most suitable medium for Candida due to its low pH and high dextrose content. 3. Low pH inhibits bacterial growth, while dextrose promotes fungal growth. 4. Zeisler media, Chocolate agar, and Muller-Hinton agar are not specific for fungal isolation. Summary: - Zeisler media is used for anaerobic bacteria. - Chocolate agar is used for fastidious organisms like Haemophilus. - Muller-Hinton agar is for antibiotic susceptibility testing, not fungal isolation.

Correct Answer: A

Rationale: The correct answer is A: Streptococcus pneumoniae. The presence of Gram-positive cocci in pairs indicates a bacterial morphology consistent with Streptococcus pneumoniae, a common cause of pneumonia. This bacterium is known to appear in pairs or short chains on Gram stain. Staphylococcus aureus (B) typically presents as clusters of Gram-positive cocci, Neisseria meningitidis (C) is a Gram-negative diplococcus, and Klebsiella pneumoniae (D) is a Gram-negative rod, making them less likely causative agents in this scenario.