microbiology chapter 1 test bank

Correct Answer: D

Rationale: Step-by-step rationale for why answer D is correct: 1. Tetanus exotoxins are produced by Clostridium tetani bacteria. 2. Once formed, the exotoxins can spread through the bloodstream. 3. Retrograde axonal transport allows the exotoxins to travel to the central nervous system (CNS). 4. In the CNS, the exotoxins can cause the symptoms of tetanus. 5. Options A, B, and C are incorrect as tetanus exotoxins do not follow those pathways. In summary, option D is correct as tetanus exotoxins can spread through the blood and reach the CNS via retrograde axonal transport, while the other options do not align with the known pathophysiology of tetanus.

Correct Answer: D

Rationale: The correct answer is D: salmonellosis. Zoonotic diseases are those that can be transmitted from animals to humans. Salmonella is not directly transmitted from animals to humans, instead, it is typically transmitted through contaminated food or water. Brucellosis (A), undulant fever (B), and plague (C) are all zoonotic diseases that can be directly transmitted from animals to humans through various means. Therefore, salmonellosis does not fit the definition of a zoonotic disease, making it the correct answer.

Correct Answer: A

Rationale: Step-by-step rationale: 1. Mycobacterium tuberculosis is the causative agent of tuberculosis. 2. Mycobacterium tuberculosis is a slow-growing, acid-fast bacterium. 3. It primarily infects the lungs and can spread to other parts of the body. 4. Bacillus anthracis causes anthrax, Clostridium tetani causes tetanus, and Treponema pallidum causes syphilis. 5. Therefore, choice A, Mycobacterium tuberculosis, is the correct answer for the bacteria responsible for tuberculosis.

Correct Answer: B

Rationale: The correct answer is B: Typhoid fever, Brucellosis. Both Typhoid fever and Brucellosis are bacterial infections that can lead to bacteremia, the presence of bacteria in the bloodstream. In Typhoid fever, the causative agent Salmonella typhi can enter the bloodstream, causing bacteremia. Similarly, Brucellosis, caused by Brucella species, can also result in bacteremia. Choice A is incorrect because bacteremia is not typically observed in Diphtheria. Choice C, Cholera, is caused by a toxin-producing bacterium and does not usually lead to bacteremia. Choice D, Dysentery, is a condition characterized by bloody diarrhea and is primarily caused by parasites or bacteria that typically do not lead to bacteremia.

Correct Answer: A

Rationale: The correct answer is A: Francisella tularensis. This bacterium is classified as a class A bioterrorism agent due to its high virulence and potential for mass casualties. It can cause tularemia, a severe and potentially fatal disease. The other choices, Hepatitis B, E. coli, and Bacillus subtilis, are not considered class A bioterrorism agents. Hepatitis B is a virus causing liver inflammation, E. coli is a common bacterium found in the gut, and Bacillus subtilis is a beneficial bacterium used in various industries. Therefore, Francisella tularensis is the correct choice based on its high pathogenicity and bioterrorism potential.