mastering microbiology test bank

Correct Answer: C

Rationale: The correct answer is C: (+RNA). This indicates that the scientist found a positive-sense RNA strand that can be directly translated by host cell machinery to produce viral proteins. Positive-sense RNA can act as messenger RNA, allowing immediate protein synthesis during viral replication. Choice A (RNA major) and D (RNA minor) are not standard terms used to describe RNA strands in virology. Choice B (-RNA) indicates a negative-sense RNA strand, which requires transcription to form a complementary positive-sense strand before protein synthesis. Thus, the identification of a strand of RNA that directly codes for viral proteins aligns with the characteristics of a positive-sense RNA strand.

Correct Answer: A

Rationale: Rationale: 1. Bacillary dysentery primarily affects the intestinal tract, not the bloodstream. 2. Bacteremia is rare in bacillary dysentery, as the infection is localized. 3. Isolating bacteria from the blood is not a typical diagnostic feature. 4. Therefore, the correct answer is A. Summary: Bacteria causing bacillary dysentery are not typically isolated from the patient's blood due to the localized nature of the infection. Choices B and C are incorrect as they suggest specific timeframes, which are not relevant to bacteremia in this context. Choice D is incorrect as bacteremia is not associated with bacillary dysentery.

Correct Answer: C

Rationale: The correct answer is C: Transcription. Transcription is the process of synthesizing RNA from a DNA template. During transcription, RNA polymerase binds to the DNA and produces a complementary RNA strand. This process is essential for gene expression. Explanation for why other choices are incorrect: A: Transposition involves the movement of genetic elements within a genome, not the production of RNA from DNA. B: Translation is the process of synthesizing proteins from mRNA, not the production of RNA from DNA. D: RNA splicing is the process of removing introns and joining exons in pre-mRNA to produce mature mRNA, not the initial production of RNA from DNA.

Correct Answer: A

Rationale: Rifampicin is the correct answer because it inhibits RNA transcription in mycobacteria by binding to the bacterial RNA polymerase. This prevents the synthesis of RNA, leading to the inhibition of protein production essential for bacterial growth. Isoniazid inhibits mycolic acid synthesis, Streptomycin inhibits protein synthesis, and Ethionamide disrupts mycolic acid synthesis. These mechanisms are different from inhibiting RNA transcription, making them incorrect choices.

Correct Answer: A

Rationale: The correct answer is A: Isoniazid and rifampicin. These drugs are considered first-line treatment for tuberculosis due to their high efficacy and low toxicity. Isoniazid targets the cell wall of the tuberculosis bacteria, while rifampicin inhibits RNA synthesis. They are recommended by WHO as the first choice for treating tuberculosis. Choice B (Penicillin and erythromycin) is incorrect because these antibiotics are not effective against tuberculosis bacteria. Choice C (Trimethoprim and third generation cephalosporins) is incorrect because they are not considered first-line drugs for tuberculosis treatment. Choice D (All the listed above can be used depending on their resistance profile) is incorrect because only isoniazid and rifampicin are universally recognized as first-line drugs for tuberculosis regardless of resistance profile.