Mastering Microbiology Test Bank

Questions 82

ATI RN

ATI RN Test Bank

Mastering Microbiology Test Bank Questions

Question 1 of 5

On the 5th day after a surgery for colon injury a patient complains of bursting pain in the postoperative wound, weakness, drowsiness, headache, fever up to 40oC. Objectively: the skin around the wound is swollen, there is gas crepitation. The wound discharges are scarce foul-smelling, of dark-gray color. What is the most likely diagnosis?

Correct Answer: A

Rationale: The correct answer is A: Anaerobic clostridial wound infection. The symptoms and signs described (bursting pain, weakness, drowsiness, fever, swollen skin, gas crepitation, foul-smelling dark-gray discharge) are classic for gas gangrene, caused by Clostridium perfringens. Gas gangrene is an anaerobic infection that thrives in devitalized tissue, such as postoperative wounds. The gas crepitation is due to gas production by the bacteria. Abscess (B) typically presents with localized swelling and fluctuance, not gas crepitation. Postoperative wound infection (C) may present with redness, warmth, and increased wound discharge but not the specific features mentioned. Erysipelas (D) is a superficial bacterial skin infection, typically caused by Streptococcus pyogenes, presenting with well-defined raised borders and redness.

Question 2 of 5

The key function of bacterial capsules is:

Correct Answer: B

Rationale: The correct answer is B: resisting phagocytosis. Bacterial capsules are composed of polysaccharides that help bacteria evade phagocytosis by immune cells. This physical barrier prevents immune cells from engulfing and destroying the bacteria. Facilitating motility (A), synthesizing DNA (C), and producing energy (D) are not primary functions of bacterial capsules. Motility is usually facilitated by flagella, DNA synthesis occurs in the bacterial chromosome, and energy production is typically carried out by metabolic processes within the bacterial cell.

Question 3 of 5

A centrifugate of urine sample obtained from patient with suspected renal tuberculosis was used to make a slide mount for microscopy. What method should be used to stain the slide and detect the causative agent?

Correct Answer: A

Rationale: The correct answer is A: Zielh-Neelsen stain. This stain is specifically used to detect acid-fast bacteria like Mycobacterium tuberculosis, the causative agent of renal tuberculosis. The staining process involves using carbol fuchsin to penetrate the mycolic acid layer of the bacterial cell wall, making it resistant to decolorization with acid-alcohol. This allows the red stained bacteria to be visualized under a microscope. Loeffler stain (B) is used for staining bacteria like diphtheria bacilli, Gram stain (C) is used for bacterial classification based on cell wall properties, and Aujeszky stain (D) is not a recognized staining method for detecting acid-fast bacteria.

Question 4 of 5

A patient with a sore throat had a throat smear stained by Neisser's method. Microscopy revealed rods with polar dark blue granules. What microorganism is likely responsible?

Correct Answer: A

Rationale: The presence of rods with polar dark blue granules stained by Neisser's method indicates metachromatic granules consistent with Corynebacterium diphtheriae. The characteristic staining pattern is due to the presence of polar granules in the bacterial cells, a feature specific to Corynebacterium diphtheriae. Bacillus anthracis, Clostridium tetani, and Escherichia coli do not exhibit this staining pattern or morphology typical of Corynebacterium diphtheriae, making them incorrect choices.

Question 5 of 5

After the second abortion a 23 year old woman has been diagnosed with toxoplasmosis. Which drug should be used for toxoplasmosis treatment?

Correct Answer: A

Rationale: The correct answer is A: Co-trimoxazole. This drug combination is the first-line treatment for toxoplasmosis due to its efficacy against Toxoplasma gondii. Co-trimoxazole consists of sulfamethoxazole and trimethoprim, which work synergistically to inhibit bacterial and protozoal folate synthesis, effectively treating toxoplasmosis. B: Itraconazole is an antifungal medication and not effective against toxoplasmosis. C: Mebendazole is an anthelmintic drug used for treating parasitic worm infections, not toxoplasmosis. D: Azidothimidine, also known as AZT, is used for treating HIV, not toxoplasmosis.

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