Pharmacology and the Nursing Process Test Bank Free

Correct Answer: B

Rationale: The correct answer is B: Probenecid (Benemid). Probenecid can increase methotrexate levels, leading to potential toxicity. Methotrexate is primarily eliminated by the kidneys, and Probenecid inhibits renal tubular secretion, causing methotrexate levels to rise. Digoxin (A), theophylline (C), and famotidine (D) do not have significant interactions with methotrexate. In summary, Probenecid is the correct answer as it can increase methotrexate levels through renal tubular secretion inhibition, while the other choices do not have a significant interaction with methotrexate.

Correct Answer: A

Rationale: The correct answer is A (5 to 10 mcg/ml) because this range is typically considered therapeutic for phenytoin (Dilantin) for seizure control. Levels below 5 mcg/ml may be subtherapeutic, leading to inadequate seizure control. Levels above 10 mcg/ml can increase the risk of toxicity. Choices B, C, and D are incorrect because they are outside the optimal therapeutic range, leading to either ineffective treatment (B, C) or an increased risk of adverse effects (D). Monitoring drug levels helps ensure the medication's effectiveness while minimizing side effects.

Correct Answer: D

Rationale: The correct answer is D because all the treatment modalities listed - surgery, radiotherapy, and chemotherapy - play essential roles in managing breast cancer. Surgery removes the primary tumor, radiotherapy targets any remaining microscopic disease, and chemotherapy systematically destroys cancer cells throughout the body. Each modality addresses a different aspect of the disease, making a comprehensive treatment approach necessary for the best outcomes. Choices A, B, and C alone do not cover all necessary aspects of breast cancer treatment, hence D is the correct choice.

Correct Answer: B

Rationale: The correct answer is B: Probenecid (Benemid). Probenecid can increase methotrexate levels, leading to potential toxicity. Methotrexate is primarily eliminated by the kidneys, and Probenecid inhibits renal tubular secretion, causing methotrexate levels to rise. Digoxin (A), theophylline (C), and famotidine (D) do not have significant interactions with methotrexate. In summary, Probenecid is the correct answer as it can increase methotrexate levels through renal tubular secretion inhibition, while the other choices do not have a significant interaction with methotrexate.

Correct Answer: B

Rationale: The correct answer is B: helicobacter pylori infection. This bacterium is a major cause of peptic ulcers by weakening the protective mucous layer of the stomach and duodenum. Research has shown a strong association between H. pylori infection and peptic ulcer development. Genetic defects in the gastric mucosa (choice A) are not a proven cause of peptic ulcers. While a high-fat diet (choice C) can exacerbate symptoms, it is not the primary cause. Work-related stress (choice D) may exacerbate symptoms but is not a direct cause of peptic ulcers. Therefore, choice B is the most supported and logical answer based on current research findings.