Proctored Pharmacology ATI

Correct Answer: B

Rationale: Nitroglycerin patches should be removed for 12 hours each day to prevent the development of tolerance. This nitrate-free interval ensures the medication remains effective in managing angina.

Correct Answer: C

Rationale: The correct answer is C. Taking aspirin along with Warfarin can increase the risk of bleeding. Clients should be advised to avoid medications that increase the risk of bleeding when taking Warfarin to prevent complications.

Correct Answer: B

Rationale: It is crucial to rotate the application site daily when using nitroglycerin patches to prevent skin irritation and ensure optimal absorption of the medication.

Correct Answer: C

Rationale: Propranolol undergoes extensive first-pass metabolism in the liver. When administered orally, propranolol is extensively metabolized by the liver before reaching systemic circulation, leading to reduced bioavailability. This process is known as first-pass hepatic metabolism, which significantly affects the drug's effectiveness and necessitates higher oral doses compared to other routes of administration.

Correct Answer: A

Rationale: Protamine sulfate is the specific antidote for Heparin. Heparin is an anticoagulant medication used to prevent blood clots, and in cases of overdose or excessive bleeding, protamine sulfate is administered to reverse its effects by neutralizing heparin's anticoagulant activity.