ATI RN
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Question 1 of 5
Which is the most prominent immunoglobulin class present in external secretions
Correct Answer: C
Rationale: The correct answer is C: IgA. IgA is the most prominent immunoglobulin class present in external secretions like saliva, tears, and mucus. It plays a crucial role in mucosal immunity by preventing pathogens from entering the body. IgG is mainly found in the blood and tissues, IgM is the first antibody produced in response to an infection, and IgE is involved in allergic reactions. IgA's presence in external secretions helps protect the body from infections at mucosal surfaces, making it the correct choice in this context.
Question 2 of 5
Which form of human plague is present with high fever and large lymphadenopathies (buboes). The case fatality in untreated cases may reach 60%.
Correct Answer: A
Rationale: The correct answer is A: Bubonic plague. Bubonic plague is characterized by high fever and large swollen lymph nodes (buboes). The case fatality rate in untreated cases can reach 60%. This form of plague is typically transmitted through the bite of an infected flea. B: Pneumonic plague presents with respiratory symptoms and is transmitted through respiratory droplets. C: Gastrointestinal plague is not a recognized form of plague. D: Septicemic plague is a severe form of plague where the bacteria multiply in the bloodstream. It may not always present with buboes.
Question 3 of 5
After a prolonged isoniazid treatment, the patient developed polyneuritis, paresthesia, memory disorders, and convulsions. What is the most likely mechanism of the described isoniazid side-effects?
Correct Answer: D
Rationale: The correct answer is D. Isoniazid inhibits pyridoxal phosphate synthesis, which is the active form of vitamin B6. Pyridoxal phosphate is essential for various enzymatic reactions, including neurotransmitter synthesis and myelin formation. Therefore, isoniazid-induced pyridoxal phosphate deficiency can lead to neurological symptoms like polyneuritis, paresthesia, memory disorders, and convulsions. A: Disruption of cell membrane synthesis - This is not the mechanism of isoniazid side-effects. B: Inhibition of protein synthesis - Isoniazid does not directly inhibit protein synthesis. C: Inhibition of RNA-synthesis - Isoniazid does not inhibit RNA synthesis; it affects vitamin B6 metabolism.
Question 4 of 5
Which fact is correct about the nucleoids in bacteria:
Correct Answer: C
Rationale: The correct answer is C because nucleoids in bacteria can vary in number from 1 to 4 depending on the specific bacterial cell and its growth and replication phases. This is due to the dynamic nature of bacterial cells and their genetic material organization. Choice A is incorrect because nucleoids do not contain nuclear membranes or multiple haploid chromosomes like eukaryotic nuclei. Choice B is incorrect as there is no known method of reabsorbing nucleoids by Neisser. Choice D is incorrect as option C is indeed the correct statement regarding the number of nucleoids in bacterial cells.
Question 5 of 5
A specific sequence of three consecutive nucleotides that is part of the genetic code and that specifies a particular amino acid in a protein or starts or stops protein synthesis is called:
Correct Answer: A
Rationale: Step 1: Definition - A codon is a sequence of three nucleotides that code for a specific amino acid or signal the start/stop of protein synthesis. Step 2: Function - Codons are essential for translating genetic information into proteins. Step 3: Specificity - Codons are specific in their role of encoding amino acids. Step 4: Examples - Examples like AUG for methionine and UAA, UAG, UGA for stop codons illustrate codon functionality. Step 5: Summary - The correct answer is A (Codon) because it accurately describes the function and specificity of a three-nucleotide sequence in genetic coding. Choices B, C, and D are incorrect as they do not align with the definition and function of a codon.
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