microbiology basic and clinical principles test bank

Correct Answer: B

Rationale: The correct answer is B: Simpler. Prokaryotic cytoplasm is simpler than eukaryotic cytoplasm because prokaryotic cells lack membrane-bound organelles such as a nucleus, mitochondria, and endoplasmic reticulum that are present in eukaryotic cells. Prokaryotic cytoplasm contains fewer components and structures compared to eukaryotic cytoplasm, making it less complex. Therefore, the prokaryotic cytoplasm is simpler in structure. Choices A, C, and D are incorrect because prokaryotic cytoplasm is not more complex than eukaryotic cytoplasm, there is a clear difference in structure between prokaryotic and eukaryotic cytoplasm, and the statement "None of the above" is not accurate as the correct answer is B.

Correct Answer: B

Rationale: The correct answer is B: Chlamydia trachomatis. This is because Chlamydia trachomatis is an obligate intracellular bacterium that cannot be cultured on standard agar plates. The symptoms described by the patient, such as pain, burning at urination, and scarce secretion in the morning, are indicative of a possible chlamydial infection. Additionally, the fact that the urine cultures are sterile after 24 hours of incubation suggests that the causative agent is not a typical bacteria like Escherichia coli, Streptococcus pneumoniae, or Neisseria gonorrhoeae, which would normally grow on agar plates. Therefore, Chlamydia trachomatis is the most probable cause of this disease. Summary: A: Escherichia coli - Incorrect, as it is a common cause of urinary tract infections and would typically grow on agar plates. C: Streptococcus pneumoniae - Incorrect, as it is

Correct Answer: A

Rationale: Ribosomes are the target for antibiotics as they interfere with protein synthesis in bacteria. Aminoglycosides, tetracyclines, macrolides, and lincosamides all target ribosomes by inhibiting protein synthesis at different stages. Beta-lactam antibiotics target cell wall synthesis, not ribosomes. Antifolate compounds, quinolones, and raspicin target DNA synthesis and replication, not ribosomes. Therefore, the correct answer is A as it includes antibiotics that specifically target ribosomes for inhibiting bacterial protein synthesis.

Correct Answer: C

Rationale: The correct answer is C because infectious (non-sterile) immunity is achieved through the persistence of the infectious agent in the body, allowing the immune system to continuously recognize and combat the pathogen. This type of immunity provides long-lasting protection against future infections by the same agent. Choice A (cross-reactivity of antibodies) is incorrect as it refers to the ability of antibodies to recognize similar antigens, not necessarily related to infectious immunity. Choice B (toxemia and formation of antitoxic antibodies) is incorrect as it specifically relates to toxins produced by pathogens and the corresponding antibody response, not the persistence of the infectious agent itself. Choice D (neutralization of infectious agent) is incorrect as it describes the process of antibodies binding to and inactivating pathogens, but it does not necessarily lead to long-term immunity through the persistence of the infectious agent.

Correct Answer: A

Rationale: The correct answer is A: ED50. The time response does not measure the ED50 because ED50 refers to the effective dose needed to produce a response in 50% of the population, which is a dose-related concept, not a time-related one. Peak effect time, onset of response, and threshold level are all time-related measures in pharmacology. Peak effect time is the time taken to reach the maximum response, onset of response is the time taken for the response to start, and threshold level is the minimum dose or concentration required to produce a response. Therefore, A is the correct answer as it is the only choice that is not a time-related measure in this context.