Endocrinology Practice Questions

Correct Answer: A

Rationale: The correct answer is A: Acute pancreatitis. Hyperparathyroidism is not typically associated with acute pancreatitis. Hyperparathyroidism is characterized by excessive production of parathyroid hormone, leading to increased calcium levels in the blood. Nephrocalcinosis, palpable neck swelling, and pseudogout are commonly seen in hyperparathyroidism due to the effects of elevated calcium levels on the kidneys, parathyroid glands, and joints, respectively. Acute pancreatitis, on the other hand, is more commonly associated with gallstones, alcohol consumption, or certain medications, rather than hyperparathyroidism.

Correct Answer: C

Rationale: The correct answer is C: SIADH. Secondary hyperaldosteronism is characterized by increased aldosterone production due to factors outside of the adrenal glands, such as increased renin-angiotensin-aldosterone system activation. SIADH does not involve aldosterone, but rather involves inappropriate secretion of antidiuretic hormone leading to hyponatremia. In contrast, congestive cardiac failure, nephrotic syndrome, and cirrhosis of the liver can all lead to secondary hyperaldosteronism due to mechanisms such as decreased effective circulating volume, renal hypoperfusion, and increased angiotensin II levels, respectively.

Correct Answer: B

Rationale: The correct answer is B: Bitemporal Hemianopsia. Pituitary adenomas can compress the optic chiasm, leading to bitemporal hemianopsia. This occurs due to the loss of peripheral vision on both sides. Carpo-pedal spasm (A) is associated with hypocalcemia, Chvostek's sign (C) is a facial spasm seen in hypocalcemia, and tremor (D) can be seen in conditions such as Parkinson's disease, but they are not specific to pituitary adenoma. Bitemporal hemianopsia is a classic sign of pituitary adenoma due to its location near the optic chiasm.

Correct Answer: D

Rationale: The correct answer is D: Thyroxine-binding globulin (TBG). TBG is the primary source of bound T4 in the plasma as it specifically binds to and transports thyroid hormones. This protein has the highest affinity for T4 compared to other plasma proteins. Albumin (A) and gamma globulins (B) can also bind to thyroid hormones, but TBG is the primary carrier. Thyroid peroxidase (C) is an enzyme involved in thyroid hormone production, not in binding T4 in the plasma.

Correct Answer: C

Rationale: Rationale: 1. GnRH directly binds to pituitary receptors. 2. GnRH specifically targets gonadotroph cells to release LH and FSH. 3. CRH and ACTH are related to stress and adrenal function, not reproductive hormones. 4. Tremor is unrelated to pituitary hormone regulation. Summary: Gonadotrophin releasing hormone (GnRH) is the correct answer as it directly stimulates the release of LH and FSH from the pituitary gland. Other choices are incorrect as they are not involved in the regulation of reproductive hormones.