ATI RN
foundations in microbiology test bank Questions
Question 1 of 5
Gram-negative rods producing blue-green pigment and a fruity odor were isolated from a wound infection. What is the causative agent?
Correct Answer: A
Rationale: The correct answer is A: Pseudomonas aeruginosa. P. aeruginosa is known for producing a blue-green pigment called pyocyanin, which gives a characteristic color to the colonies. The fruity odor is due to the production of a compound called 2-aminoacetophenone by P. aeruginosa. These features are classic for P. aeruginosa and help differentiate it from other Gram-negative rods. Proteus mirabilis (B) typically does not produce blue-green pigment or fruity odor. Klebsiella pneumoniae (C) and Escherichia coli (D) also do not exhibit these specific characteristics associated with P. aeruginosa.
Question 2 of 5
Examination of a smear from a chancre revealed mobile, long, spiral microorganisms with 8-12 regular coils. What is the causative agent?
Correct Answer: A
Rationale: The correct answer is A: Treponema. The characteristics described match Treponema pallidum, the causative agent of syphilis. Treponema has long, spiral shape with 8-12 regular coils. Leptospira (B) is a spirochete but has fewer coils and causes leptospirosis. Borrelia (C) is another spirochete but typically has irregular coils and causes Lyme disease. Vibrios (D) are curved rods and not spirochetes.
Question 3 of 5
Allergy to penicillin is an example of:
Correct Answer: A
Rationale: Step-by-step rationale for choice A being correct: 1. Penicillin allergy involves IgE antibodies binding to penicillin. 2. This triggers mast cell degranulation, releasing histamine. 3. Histamine causes allergic symptoms like rash, swelling. 4. This immune response characterizes Type I hypersensitivity reactions. Summary of other choices: B: Type II reactions involve antibody-mediated cell destruction, not seen in penicillin allergy. C: Type III reactions involve immune complex deposition, not typical in penicillin allergy. D: Type IV reactions are delayed hypersensitivity reactions, not immediate like penicillin allergy.
Question 4 of 5
The complex of non-specific innate defense factors acting against number of infectious agents is known as:
Correct Answer: D
Rationale: The correct answer is D: Innate immunity (natural resistance). Innate immunity refers to the non-specific defense mechanisms that act against a variety of infectious agents. This includes physical barriers like skin and mucous membranes, as well as cellular components like phagocytes and natural killer cells. Adaptive immunity (A) is specific and involves the production of antibodies and immune memory (B), which are not part of the initial non-specific response. Antibodies (C) are part of the adaptive immune response and are produced in response to specific pathogens, not part of the non-specific innate defense factors.
Question 5 of 5
The causative agent of plague is:
Correct Answer: B
Rationale: The correct answer is B: Yersinia pestis. Y. pestis is the causative agent of plague, a serious infectious disease transmitted through fleas. It causes bubonic, pneumonic, and septicemic plague. Bordetella pertussis causes whooping cough, Rickettsia prowazekii causes epidemic typhus, and Treponema pallidum causes syphilis. Y. pestis is the correct answer because it is specifically associated with plague, making the other options incorrect.
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