Microbiology Chapter 12 Test Bank

Correct Answer: A

Rationale: The correct answer is A: Serological. Serological testing involves analyzing blood samples for specific antibodies produced in response to the pertussis infection. This method can detect past infections by identifying the presence of antibodies against the pertussis bacteria in the blood. In this case, since the doctor suspects pertussis infection in both children, serological testing can confirm if they have been exposed to the bacteria. Summary: B: Biological testing does not specifically target pertussis antibodies in the blood. C: Bacteriological testing involves culturing bacteria from samples, which may not be as sensitive for retrospective diagnosis. D: Molecular biological testing focuses on genetic material of the bacteria, which may not provide direct evidence of past infection.

Correct Answer: A

Rationale: Step 1: Gram-positive diplococci suggest a pneumococcal infection. Step 2: Catalase-negative indicates Streptococcus. Step 3: Alpha-hemolysis matches S. pneumoniae's characteristics. Therefore, Streptococcus pneumoniae is the most likely causative agent. Staphylococcus aureus (B) is catalase-positive, Neisseria meningitidis (C) is Gram-negative, and Klebsiella pneumoniae (D) is not diplococci or alpha-hemolytic.

Correct Answer: A

Rationale: The presence of flagella in a bacterial cell represents the H-antigen. Flagella are protein structures on the cell surface that play a role in bacterial motility. The H-antigen refers to the flagellar antigen, which is involved in immune responses and bacterial identification. Option A is correct because flagella are specifically associated with the H-antigen. Summarily, choices B and C are incorrect because the O-antigen and K-antigen are associated with lipopolysaccharide and capsule antigens, respectively, not flagella. Option D is incorrect as well because the correct association is with the H-antigen.

Correct Answer: B

Rationale: The correct answer is B: bioavailability. Bioavailability refers to the extent and rate at which a drug reaches its site of action in the body. This includes factors such as absorption, distribution, metabolism, and excretion. Rationale: 1. Bioactivity refers to the pharmacological effect of a drug, not how effectively it reaches its site of action. 2. Bioremediation is the process of using organisms to remove or neutralize pollutants, not related to drug delivery. 3. Biostasis refers to a state of equilibrium or balance in living organisms, not related to drug transport to its site of action. In summary, bioavailability is the most appropriate term as it specifically addresses the process of a drug reaching its intended target within the body, distinguishing it from the other choices.

Correct Answer: D

Rationale: The correct answer is D: All of the above. Hepatitis B infection can present with jaundice due to liver inflammation, elevated serum aminotransferase levels due to liver damage, and sometimes no symptoms in the acute phase. This comprehensive presentation covers the spectrum of possible clinical manifestations of hepatitis B infection. Choices A and B are correct as they are common manifestations of hepatitis B infection. Choice C is incorrect as hepatitis B infection can indeed present with symptoms, making option D the most appropriate choice.