Microbiology Chapter 12 Test Bank

Correct Answer: A

Rationale: The correct answer is A: Type IV hypersensitivity reaction. This type of reaction is characterized by a delayed response involving T cells. In this case, the appearance of a papule after 48 hours indicates a delayed hypersensitivity reaction, which is typical of a Type IV reaction. The other choices are incorrect because: B: Arthus phenomenon is a localized immune complex-mediated reaction, not seen in tuberculin tests. C: Seroreaction typically involves antibodies reacting with soluble antigens, not seen in this scenario. D: Type II hypersensitivity reactions involve antibodies targeting specific cells or tissues, which is not the mechanism at play in this case.

Correct Answer: B

Rationale: The correct answer is B: abiogenesis. Spontaneous generation refers to the idea that living organisms can arise from non-living matter, which was disproven by Louis Pasteur. Abiogenesis specifically refers to the origin of life from non-living matter, making it synonymous with spontaneous generation. Biogenesis (A) is the principle that living organisms only come from other living organisms. Evolution (C) is the process of gradual change in species over time. Spontaneity (D) refers to happening without external cause and is not directly related to the concept of spontaneous generation.

Correct Answer: D

Rationale: The correct answer is D: Immunocomplex. In this case, the patient's symptoms of fever, joint pains, rash, and itch along with leukopenia and thrombocytopenia indicate a serum sickness reaction. This is a type III hypersensitivity reaction where antigen-antibody complexes deposit in tissues, leading to inflammation and tissue damage. The symptoms typically occur 1-2 weeks after exposure to the antigen. Anaphylactic reaction (choice A) is immediate and involves IgE antibodies. Cytotoxic reaction (choice B) involves destruction of cells by antibodies. Delayed hypersensitivity (choice C) usually takes 48-72 hours to develop and involves T-cells. Therefore, the correct answer is D as it aligns with the symptoms and timeline of a type III hypersensitivity reaction.

Correct Answer: B

Rationale: Bacillary dysentery is caused by the bacterium Shigella, hence it is also known as shigellosis. Shigella is the primary pathogen responsible for this infectious disease, leading to severe diarrhea with blood and mucus. Salmonellosis (A) is caused by Salmonella bacteria, not Shigella. Typhoid fever (C) is caused by Salmonella typhi, not Shigella. Campylobacteriosis (D) is caused by Campylobacter bacteria, not Shigella. Therefore, the correct answer is B because Shigella is the specific bacterium associated with bacillary dysentery.

Correct Answer: D

Rationale: The correct answer is D: metronidazole. Metronidazole is specifically effective against protozoan infections due to its ability to target and disrupt the DNA of the parasites. It is commonly used to treat infections such as trichomoniasis and giardiasis that affect the reproductive system. Ampicillin (A) and tetracycline (B) are antibiotics that target bacteria, not protozoa. Ciprofloxacin (C) is also an antibiotic that is effective against certain bacterial infections but not protozoan infections. Therefore, metronidazole is the most appropriate choice for fighting protozoan infections of the reproductive system.