Pharmacology and the Nursing Process 10th Edition Test Bank

Correct Answer: B

Rationale: The correct answer is B: I.V. administration and urinary excretion. Lomustine is typically administered intravenously, allowing for rapid systemic distribution. The drug is metabolized in the liver and excreted primarily through the kidneys, thus the urinary route. This choice is correct as lomustine's pharmacokinetics align with this pattern. A: Oral administration and urinary - While some drugs are administered orally, lomustine is not typically given orally due to poor bioavailability. C: I.V. administration and fecal excretion - Lomustine is not primarily excreted via the feces, making this choice incorrect. D: Oral administration and fecal excretion - Lomustine is not primarily excreted via the feces, making this choice incorrect.

Correct Answer: B

Rationale: The correct answer is B: Ototoxic. Ototoxic refers to substances that are harmful to the ear, potentially causing hearing loss or damage. The prefix "oto-" specifically relates to the ear. Otoplasty (A) is a surgical procedure to reshape the ear, not related to toxicity. Otalgia (C) refers to ear pain, not toxicity. Tinnitus (D) is a symptom of ringing in the ears, not directly related to toxicity. Therefore, the term "ototoxic" is the best indicator of a substance being toxic to the ear due to its specific reference to ear toxicity.

Correct Answer: A

Rationale: The correct answer is A: Hypocortisolism. After a transsphenoidal hypophysectomy, the pituitary gland is removed or partially removed, leading to decreased cortisol production. Signs of hypocortisolism include weakness, fatigue, hypotension, weight loss, and electrolyte imbalances. Hyperglycemia (B) is not typically associated with this procedure. Hypoglycemia (C) is not a common concern post-hypophysectomy. Hypercalcemia (D) is not directly related to pituitary gland removal. Therefore, assessing for hypocortisolism is crucial for early detection and management post-surgery.

Correct Answer: A

Rationale: The correct answer is A: Hair loss. Radiation therapy targets fast-growing cancer cells, which can also affect healthy cells such as those in hair follicles, leading to hair loss. This adverse effect occurs commonly with radiation therapy due to its impact on rapidly dividing cells. Hair loss is a well-known side effect that clients undergoing radiation therapy are often prepared for. The other choices, B: Fatigue, C: Stomatitis, and D: Vomiting, are also potential side effects of radiation therapy, but hair loss is specifically associated with radiation treatment due to its effect on hair follicles. Fatigue is a common side effect of cancer treatment in general, stomatitis is more commonly associated with chemotherapy, and vomiting can be a side effect of radiation but is not as directly linked as hair loss.

Correct Answer: C

Rationale: Step-by-step rationale for choice C being correct: 1. Restlessness: Indicates increased work of breathing and hypoxia. 2. Suprasternal retractions: Sign of respiratory distress. 3. paO2 of 62: Indicates severe hypoxemia, common in ARDS. Summary: A: Enlarged heart on x-ray does not directly indicate ARDS. B: Thick green sputum suggests infection, not specific to ARDS. D: Wheezes and slow respirations are not typical of ARDS, and pCO2 is normal in ARDS.