Microbiology A Systems Approach Test Bank

Correct Answer: D

Rationale: The most likely diagnosis is D: Lymphocutaneous tularemia. The key clues include exposure to a dead animal, vesicle with serosanginous exudate, painless edema progressing to lymph node involvement, and fever. Tularemia is caused by Francisella tularensis, commonly acquired through contact with infected animals. The characteristic ulcer at the site of entry, lymphadenopathy, and systemic symptoms point towards tularemia. Cutaneous anthrax (A) presents with a painless ulcer and black eschar. Bubonic plague (B) typically presents with buboes (swollen lymph nodes) and fever. Carbuncle (C) is a deep skin infection typically caused by Staphylococcus aureus.

Correct Answer: D

Rationale: The correct answer is D: All of the above. Neisseria meningitidis, Haemophilus influenzae, and Streptococcus pneumoniae are all bacteria associated with causing bacterial meningitis. Neisseria meningitidis commonly causes meningococcal meningitis, Haemophilus influenzae can cause H. influenzae type b meningitis, and Streptococcus pneumoniae is a common cause of pneumococcal meningitis. Therefore, all three bacteria are known to be causative agents of bacterial meningitis. The other choices are incorrect as they do not encompass all the bacteria associated with causing bacterial meningitis.

Correct Answer: C

Rationale: Rationale for Correct Answer (C - Immunity): 1. Immunity refers to the body's ability to defend against foreign agents. 2. Homeostasis is the state of steady internal conditions, not specifically related to defense. 3. Infection is the invasion and multiplication of pathogens, not the overall defense mechanism. 4. Commensalism is a symbiotic relationship where one organism benefits without harming the other.

Correct Answer: D

Rationale: The correct answer is D because all three choices, Clostridium botulinum, Morbillivirus morbillorum, and Clostridium tetani, can cause infections of the CNS. Clostridium botulinum can lead to botulism, affecting the nervous system. Morbillivirus morbillorum can cause measles, which can lead to encephalitis. Clostridium tetani can cause tetanus, affecting the central nervous system. Therefore, all three choices can cause infections of the CNS. Choices A, B, and C are incorrect individually because each pathogen can cause CNS infections.

Correct Answer: A

Rationale: The correct answer is A: Rifampicin. Rifampicin is known to cause red discoloration of bodily fluids, including tears and urine, due to its side effect of harmless color changes. Benzylpenicillins (B and C) and Biseptol-480 do not typically cause such discoloration. Rifampicin's mechanism of action involves binding to bacterial RNA polymerase, leading to inhibition of RNA synthesis, which is unrelated to the mechanism of the other drugs. Thus, based on the unique side effect profile of Rifampicin and its mechanism of action, it is the most likely drug causing red tears and urine in this scenario.