Microbiology Basic and Clinical Principles Test Bank

Correct Answer: A

Rationale: The most likely diagnosis is A: Pneumonic plague. The patient's symptoms align with the presentation of pneumonic plague, caused by the bacterium Yersinia pestis. Symptoms include high fever, severe headache, dyspnea, cough with bloody sputum, and cyanosis. The characteristic bubonic plague lymphadenopathy may be absent in the pneumonic form. The patient's recent travel history to India also raises suspicion, as plague is endemic in some regions. The other choices can be ruled out based on the patient's symptoms and presentation. Miliary tuberculosis typically presents with diffuse miliary nodules on imaging. Influenza typically presents with more generalized symptoms and does not usually cause rusty sputum. Ornithosis is caused by Chlamydophila psittaci and usually presents with pneumonia-like symptoms after exposure to infected birds.

Correct Answer: B

Rationale: The correct answer is B: Vibrio cholerae. Cholera is caused by Vibrio cholerae, a bacterium that infects the small intestine, leading to severe diarrhea and dehydration. This bacterium produces a toxin that causes the symptoms of cholera. A: Shigella dysenteriae causes dysentery, not cholera. C: Salmonella enterica causes food poisoning, not cholera. D: Escherichia coli can cause food poisoning but not cholera.

Correct Answer: D

Rationale: The correct answer is D (All of the above) because all three bacteria listed produce exotoxins that cause severe gastrointestinal illness. Clostridium botulinum produces botulinum toxin causing botulism. Vibrio cholerae produces cholera toxin leading to cholera. Escherichia coli can produce various exotoxins causing different types of severe gastrointestinal illnesses like E. coli O157:H7 causing bloody diarrhea. Therefore, all choices A, B, and C are correct in this case as they all produce exotoxins causing severe gastrointestinal illness.

Correct Answer: A

Rationale: The correct answer is A: Neisseria meningitidis. This is because Neisseria meningitidis is a Gram-negative diplococcus known to cause bacterial meningitis, presenting with fever, headache, and neck stiffness. It is a common cause of meningitis in young adults and teenagers. Streptococcus pneumoniae (B) is a Gram-positive bacteria and a common cause of bacterial pneumonia, not meningitis. Haemophilus influenzae (C) is a Gram-negative coccobacillus that can cause meningitis, but it is less common in adults. Klebsiella pneumoniae (D) is a Gram-negative bacillus known to cause pneumonia and urinary tract infections, not meningitis.

Correct Answer: B

Rationale: The correct answer is B: Yersinia pestis. Yersinia pestis is the bacterium responsible for causing the plague, specifically the bubonic plague. It is transmitted through fleas and rodents. Escherichia coli (A) is a common gut bacterium, Clostridium difficile (C) causes antibiotic-associated diarrhea, and Staphylococcus aureus (D) is associated with skin infections, but they are not responsible for causing the plague.