medical microbiology test bank

Correct Answer: D

Rationale: The correct answer is D because all of the symptoms mentioned (short period of depression, nausea, restlessness) can be early signs of rabies. Rabies typically presents with a variety of non-specific symptoms in the early stages, including behavioral changes such as depression and restlessness, as well as gastrointestinal symptoms like nausea. Therefore, it is important to consider the combination of these symptoms collectively rather than individually when suspecting rabies. Choices A, B, and C alone may not definitively indicate rabies, but when seen together, they should raise suspicion and prompt further evaluation and testing for rabies.

Correct Answer: A

Rationale: The correct answer is A: Rifampicin. Rifampicin can cause red-orange discoloration of bodily fluids like urine due to its metabolism. This phenomenon is harmless but alarming to patients. Isoniazid (B) can cause peripheral neuropathy, Pyrazinamide (C) can cause hyperuricemia, and Ethambutol (D) can cause optic neuropathy.

Correct Answer: D

Rationale: The correct answer is D: Pulmonary tuberculosis. The presence of red bacilli stained with Ziehl-Nielsen method indicates acid-fast bacteria, which are characteristic of Mycobacterium tuberculosis, the causative agent of tuberculosis. The size and appearance of the bacilli described match those of M. tuberculosis. Chronic pneumonia, along with the specific staining pattern, strongly suggests tuberculosis as the likely diagnosis. Explanation for other choices: A: Pneumococcal pneumonia is caused by Streptococcus pneumoniae, which would not show red bacilli on Ziehl-Nielsen staining. B: Pulmonary actinomycosis is caused by Actinomyces species, not acid-fast bacteria like M. tuberculosis. C: Pulmonary candidiasis is caused by Candida species, which are fungi and do not appear as red bacilli on staining.

Correct Answer: D

Rationale: The correct answer is D: Gram-negative coccobacillus. Francisella tularensis is a Gram-negative coccobacillus because it has a unique shape that is between a coccus (spherical) and a bacillus (rod-shaped) and it stains pink/red in the Gram staining process. It is important to note that it is not a coccus (choice B) or a Gram-positive bacterium (choice A). Choice C is too general and does not specify the coccobacillus shape of F. tularensis. So, the correct answer is D due to its specific characteristics as a Gram-negative coccobacillus.

Correct Answer: B

Rationale: The correct answer is B: Clostridium botulinum. This bacterium produces the botulinum toxin, which causes botulism by blocking nerve functions. Clostridium tetani causes tetanus, not botulism. Staphylococcus aureus produces toxins that cause food poisoning, not botulism. Bacillus anthracis causes anthrax, not botulism. Therefore, the correct choice is Clostridium botulinum because it is the specific bacterium responsible for producing the toxin that leads to botulism.