microbiology chapter 11 test bank

Correct Answer: B

Rationale: The correct answer is B: Reverse transcriptase and protease. Reverse transcriptase converts viral RNA into DNA, a crucial step in viral replication. Protease is responsible for cleaving viral polyproteins into functional proteins. Targeting both enzymes disrupts viral replication. Choice A is incorrect as integrase is not a main target in current therapy. Choice C is incorrect because protease is targeted along with reverse transcriptase, not integrase. Choice D is incorrect as targeting viral glycoproteins is not a main strategy in anti-HIV therapy.

Correct Answer: D

Rationale: The correct answer is D: Middlebrook's medium. This medium is specifically designed for the growth of Mycobacterium tuberculosis due to its low concentration of malachite green, which inhibits the growth of other bacteria but not Mycobacterium species. Middlebrook's medium also contains various nutrients that support the growth of Mycobacterium tuberculosis. A: Middlebrook's medium is the correct answer, not incorrect. B: Heart infusion broth is a general-purpose medium, not specific for Mycobacterium tuberculosis. C: MacConkey agar is selective for gram-negative bacteria and would not support the growth of Mycobacterium tuberculosis. In summary, Middlebrook's medium is the ideal choice for cultivating Mycobacterium tuberculosis due to its specific formulation that promotes the growth of this pathogen while inhibiting other bacteria.

Correct Answer: A

Rationale: Axial filaments, also known as endoflagella, are composed of proteins. These proteins form a helical structure that enables certain bacteria, such as spirochetes, to move in a corkscrew-like motion. Proteins are the main structural component of axial filaments due to their flexibility and ability to generate movement. Choice B, polyphosphates, are not typically associated with axial filaments, as they are more involved in energy storage and transfer. Choice C, volutin granules, are storage inclusions of inorganic polyphosphate and are not part of axial filaments. Choice D, carbohydrates, are not the primary component of axial filaments which are protein-based structures responsible for bacterial motility.

Correct Answer: D

Rationale: The correct answer is D: All of the above. Hospital-acquired infections can be caused by a variety of bacteria commonly found in healthcare settings. Staphylococcus aureus is a common cause of surgical site infections. Escherichia coli can cause urinary tract infections. Klebsiella pneumoniae is associated with pneumonia and bloodstream infections. Therefore, all three bacteria are frequently implicated in hospital-acquired infections due to their prevalence and ability to cause different types of infections in healthcare settings. Thus, the correct answer is D, as all of the listed bacteria are commonly associated with hospital-acquired infections.

Correct Answer: B

Rationale: The correct answer is B: Mycobacterium tuberculosis. This bacterium is specifically associated with causing tuberculosis. Mycobacterium leprae (choice A) is associated with leprosy, not tuberculosis. Streptococcus pneumoniae (choice C) is associated with pneumonia, not tuberculosis. Escherichia coli (choice D) is a common bacterium found in the intestines and is not associated with tuberculosis. Mycobacterium tuberculosis is the only bacterium directly linked to the disease, making it the correct choice.