microbiology chapter 12 test bank

Correct Answer: A

Rationale: The correct answer is A because Shigella sonnei escapes phagocytic clearance by lysing the phagosome and replicating in the cytoplasm. This allows the bacterium to avoid being destroyed by the acidic environment and enzymes in the phagolysosome. Choice B is incorrect as Shigella does not have a capsule. Choice C is incorrect because Shigella actually induces phagosome-lysosome fusion to facilitate its escape. Choice D is incorrect as protein A is a component of Staphylococcus aureus, not Shigella sonnei.

Correct Answer: D

Rationale: The correct answer is D: peroxisomes. Peroxisomes contain oxidative enzymes, such as catalase and peroxidase, that are capable of oxidizing toxic substances. These enzymes help detoxify harmful molecules by breaking them down into harmless products. Lysosomes (choices B and C) contain hydrolytic enzymes for breaking down cellular waste, not oxidative enzymes. Therefore, the correct choice is peroxisomes due to their specific function in detoxification through oxidation reactions.

Correct Answer: B

Rationale: The correct answer is B: Agglutination reaction. This is the most suitable serological reaction for the quick determination of the antigen of the epizootic agent causing mass rodent deaths. In agglutination reaction, antibodies cause the clumping of antigens, allowing for easy visual detection of the presence of the specific antigen. This is efficient for rapid diagnosis in cases of suspected infectious diseases like plague. A: Precipitation reaction is more suitable for identifying soluble antigens, not for quick determination of a specific antigen in this scenario. C: Reaction of passive hemagglutination is used for measuring the presence of antibodies, not antigens. D: Bordet-Gengou test is a specific test for the identification of Bordetella pertussis bacterium, not suitable for this scenario.

Correct Answer: B

Rationale: Rationale: The correct answer is B. Viruses of the family Paramyxoviridae cause the formation of giant multinucleated cells called syncytia. This occurs when infected cells fuse together, resulting in large, multinucleated structures. This is a characteristic cytopathic effect of paramyxoviruses. Summary: A: Fine grained degeneration is not typically seen in paramyxovirus infections. C: Large cell degeneration with grape clustering of cells is not a typical cytopathic effect of paramyxoviruses. D: Paramyxoviruses do provoke a cytopathic effect, so this statement is incorrect.

Correct Answer: D

Rationale: The correct answer is D: Non-tender chancre (ulcus durum). In the primary stage of syphilis, an individual typically develops a painless ulcer known as a chancre at the site of infection. This ulcer is usually firm, round, and clean with well-defined borders. It is important to note that it is non-tender, which distinguishes it from other skin conditions. This characteristic helps healthcare providers differentiate syphilis from other sexually transmitted infections. Explanation for other choices: A: Diffuse maculopapular rash - This is more commonly associated with secondary syphilis. B: Purulent exudation from the urethra - This is not a typical presentation of primary syphilis. C: Syphilitic granulomas (gummas) - Gummas typically develop in the tertiary stage of syphilis, not in the primary stage.