microbiology basic and clinical principles test bank

Correct Answer: B

Rationale: During latency, HSV1 exists as episomes in neurons. This is because HSV1 establishes a lifelong latent infection in sensory neurons, where the viral genome remains as a circular episome in the nucleus. This form allows the virus to persist in a dormant state, avoiding detection by the immune system. Choice A is incorrect as HSV1 does not integrate into the host chromosome. Choice C is incorrect as latency is a well-documented phenomenon for HSV1. Choice D is incorrect as the correct answer is B.

Correct Answer: A

Rationale: The correct answer is A: Vibrios. Vibrios are gram-negative curved bacteria that are motile and do not form spores or capsules. The description of the bacteria in the question fits the characteristics of Vibrios. Vibrios are commonly found in aquatic environments and some species can cause gastrointestinal infections in humans. B: Spirochetes are also gram-negative curved bacteria, but they are spiral-shaped and have unique axial filaments for motility. The description in the question does not match the characteristics of spirochetes. C: Clostridia are gram-positive, spore-forming bacteria. The question specifically states that the bacteria are gram-negative and do not form spores, ruling out Clostridia. D: Corynebacteria are gram-positive, non-spore-forming bacteria. The description in the question does not match the characteristics of Corynebacteria.

Correct Answer: A

Rationale: The correct answer is A: BCG. BCG vaccine is commonly used for tuberculosis prevention because it provides immunity against Mycobacterium tuberculosis. Mantoux is a test, not a vaccine. DTaP vaccine is for diphtheria, tetanus, and pertussis, not tuberculosis. Anatoxin is a type of toxoid vaccine, not used for tuberculosis prevention. BCG vaccine has been shown to be effective in preventing severe forms of tuberculosis in infants, making it the appropriate choice in this scenario.

Correct Answer: A

Rationale: Ribosomes are the target for antibiotics as they interfere with protein synthesis in bacteria. Aminoglycosides, tetracyclines, macrolides, and lincosamides all target ribosomes by inhibiting protein synthesis at different stages. Beta-lactam antibiotics target cell wall synthesis, not ribosomes. Antifolate compounds, quinolones, and raspicin target DNA synthesis and replication, not ribosomes. Therefore, the correct answer is A as it includes antibiotics that specifically target ribosomes for inhibiting bacterial protein synthesis.

Correct Answer: B

Rationale: The correct answer is B: non-spore forming encapsulated gram-negative bacterium. Francisella tularensis is a non-spore forming bacterium, which rules out choices A and D. It is encapsulated, which eliminates choice C. The encapsulation of the bacterium helps it evade the host immune system, leading to its pathogenicity. This encapsulated bacterium is responsible for causing the zoonotic disease tularemia in humans.