Medical Microbiology Test Bank

Correct Answer: A

Rationale: Step-by-step rationale: 1. Metronidazole is a synthetic antiprotozoal drug commonly used for wound infection prevention. 2. It is highly effective against Helicobacter pylori, a bacterium that causes stomach ulcers. 3. Metronidazole works by disrupting DNA structure in bacteria, leading to their death. 4. Chingamin (Chloroquine) is an antimalarial drug, not effective against Helicobacter pylori. 5. Doxycycline hydrochloride is an antibiotic used for bacterial infections, not specifically for H. pylori. 6. Aciclovir is an antiviral drug used for herpes infections, not effective against H. pylori. Summary: Metronidazole is the correct answer as it is specifically effective against H. pylori and commonly used for wound infection prevention. Other choices are incorrect as they target different types of infections.

Correct Answer: D

Rationale: The correct answer is D: Pulmonary tuberculosis. The presence of red bacilli stained with Ziehl-Nielsen method indicates acid-fast bacteria, which are characteristic of Mycobacterium tuberculosis, the causative agent of tuberculosis. The size and appearance of the bacilli described match those of M. tuberculosis. Chronic pneumonia, along with the specific staining pattern, strongly suggests tuberculosis as the likely diagnosis. Explanation for other choices: A: Pneumococcal pneumonia is caused by Streptococcus pneumoniae, which would not show red bacilli on Ziehl-Nielsen staining. B: Pulmonary actinomycosis is caused by Actinomyces species, not acid-fast bacteria like M. tuberculosis. C: Pulmonary candidiasis is caused by Candida species, which are fungi and do not appear as red bacilli on staining.

Correct Answer: B

Rationale: The correct answer is B because the AST reaction, or anti-streptolysin titer, is used in the diagnostic of post-streptococcal sequelae, such as rheumatic fever and glomerulonephritis. This test measures the level of antibodies produced by the body in response to Streptolysin O, a toxin produced by Group A Streptococcus bacteria. It helps in identifying if a patient has had a recent Streptococcus infection that could lead to these complications. A: Incorrect. The AST reaction does not require urine samples, but rather blood samples. C: Incorrect. The AST reaction specifically targets antibodies produced in response to Group A Streptococcus. D: Incorrect. The AST reaction does not directly identify isolated streptococci but rather measures the body's immune response to Streptolysin O.

Correct Answer: A

Rationale: The correct answer is A: Centers for Disease Control and Prevention. The CDC is a U.S. government agency responsible for protecting public health and safety. The correct answer is the only choice that accurately reflects the agency's purpose. Choice B (Children's Disease Center) is incorrect because the CDC's scope is not limited to children's health. Choice C (Central Disaster Control Center) is incorrect as the CDC primarily focuses on disease prevention. Choice D (Central Drug Evaluation and Control Center) is incorrect as the CDC's main focus is not on drug evaluation. Thus, the correct answer is A as it aligns with the CDC's mission and responsibilities.

Correct Answer: A

Rationale: Step 1: Legionellosis is caused by the Legionella bacteria. Step 2: Legionellosis has two main clinical forms - Legionnaires disease and Pontiac fever. Step 3: Legionnaires disease presents with severe pneumonia symptoms, while Pontiac fever is a milder flu-like illness. Step 4: Therefore, the correct answer is A: Legionnaires disease and Pontiac fever. Summary: - Choice B (Skin and intestinal form) is incorrect as Legionellosis primarily affects the lungs. - Choice C (Lymphatic, lung, and intestinal forms) is incorrect as it does not accurately represent the clinical forms of Legionellosis. - Choice D (None of the above) is incorrect as Legionellosis does have specific clinical forms.