Foundations in Microbiology Test Bank

Correct Answer: A

Rationale: The correct answer is A: Syphilis. The presentation of painless inguinal lymph nodes, along with a small-sized ulcer with thickened edges and a "laquer" bottom of greyish color on the genital mucous membrane, is classic for primary syphilis. The painless nature of the lymph nodes and the specific characteristics of the ulcer are key features of syphilitic infection. Primary syphilis is caused by the bacterium Treponema pallidum and typically presents with a single, painless ulcer known as a chancre. It is important to consider syphilis in the differential diagnosis of genital ulcers. Summary of other choices: B: Tuberculosis - Unlikely, as tuberculosis typically presents with pulmonary symptoms and does not cause genital ulcers. C: Lepra - Unlikely, as leprosy does not typically present with painless inguinal lymph nodes and the specific ulcer characteristics described. D: Trophic ulcer - Unlikely

Correct Answer: A

Rationale: The correct answer is A because adaptive immunity is not mainly observed in the skin and mucous membranes. Adaptive immunity is a systemic response that involves specific immune cells and antibodies targeting specific pathogens. It develops immune memory (B), meaning it can recognize and respond faster upon re-exposure to the same pathogen. Adaptive immunity also has specificity (C), as it can target specific antigens. Lastly, adaptive immunity is not evolutionarily newer in comparison to innate immunity (D), as both systems have co-evolved to provide comprehensive protection against pathogens.

Correct Answer: B

Rationale: The correct answer is B: Chlamydia trachomatis. Elementary bodies (EBs) and reticular bodies (RBs) are two distinct forms of Chlamydia trachomatis, a bacterium causing various infections. EBs are the infectious form, while RBs are the replicative form within host cells. Mycoplasma genitalium (choice A) lacks a cell wall and does not have these specific morphological forms. Rickettsia prowazekii (choice C) is an obligate intracellular bacterium but does not exhibit the elementary and reticular body forms characteristic of Chlamydia trachomatis. Therefore, the correct answer is B, as only Chlamydia trachomatis exhibits the elementary and reticular bodies.

Correct Answer: C

Rationale: Step 1: Togaviridae is a family of viruses known to have non-segmented (+)ssRNA as their genetic material. Step 2: The positive sense RNA means that the viral RNA can be directly translated into proteins by host machinery. Step 3: This RNA genome acts as mRNA, allowing for immediate translation of viral proteins. Step 4: Therefore, choice C is correct as it accurately describes the genetic nature of Togaviridae. Summary: - Choice A is incorrect because Togaviridae viruses do not have helical symmetry. - Choice B is incorrect because Togaviridae viruses do not have non-segmented (-)dsRNA. - Choice D is incorrect because Togaviridae viruses are enveloped viruses.

Correct Answer: B

Rationale: The correct answer is B: K-antigen. H. Influenzae types are classified based on their capsular polysaccharides, which are known as K-antigens. The K-antigen is a major virulence factor and plays a crucial role in the pathogenicity of H. Influenzae. The other options (A, C, D) are not used to classify H. Influenzae types. Vi-antigen is related to Salmonella serotyping, O-antigen is characteristic of gram-negative bacteria such as Escherichia coli and Salmonella, and H-antigen is typically associated with flagellar antigens of bacteria like Salmonella and E. coli.