ATI RN
microbiology basic and clinical principles test bank Questions
Question 1 of 5
A patient with fever, headache, and neck stiffness had a cerebrospinal fluid sample showing Gram-negative diplococci. What is the most likely causative agent?
Correct Answer: A
Rationale: The correct answer is A: Neisseria meningitidis. This is because Neisseria meningitidis is a Gram-negative diplococcus known to cause bacterial meningitis, presenting with fever, headache, and neck stiffness. It is a common cause of meningitis in young adults and teenagers. Streptococcus pneumoniae (B) is a Gram-positive bacteria and a common cause of bacterial pneumonia, not meningitis. Haemophilus influenzae (C) is a Gram-negative coccobacillus that can cause meningitis, but it is less common in adults. Klebsiella pneumoniae (D) is a Gram-negative bacillus known to cause pneumonia and urinary tract infections, not meningitis.
Question 2 of 5
What reaction is catalyzed by a beta-lactamase enzyme
Correct Answer: C
Rationale: The correct answer is C: the hydrolysis of the four-membered ring present in penicillin. Beta-lactamase enzyme catalyzes the hydrolysis of the four-membered beta-lactam ring present in penicillin, rendering the antibiotic ineffective against bacterial cell walls. This enzyme breaks the bond in the beta-lactam ring, thus inactivating the antibiotic. Incorrect choices: A: the final cross-linking reaction to form the bacterial cell wall - This is incorrect as beta-lactamase does not participate in the formation of bacterial cell walls. B: the biosynthesis of the penicillin structure from the amino acid valine and cysteine - This is incorrect as beta-lactamase is not involved in the biosynthesis of penicillin. D: the hydrolysis of the acyl side chain from penicillin structures - This is incorrect as beta-lactamase specifically targets the beta-lactam ring, not the
Question 3 of 5
Francisella tularensis is a:
Correct Answer: B
Rationale: The correct answer is B: non-spore forming encapsulated gram-negative bacterium. Francisella tularensis is a non-spore forming bacterium, which rules out choices A and D. It is encapsulated, which eliminates choice C. The encapsulation of the bacterium helps it evade the host immune system, leading to its pathogenicity. This encapsulated bacterium is responsible for causing the zoonotic disease tularemia in humans.
Question 4 of 5
The most commonly acquired laboratory infections are caused by
Correct Answer: A
Rationale: The correct answer is A: bacteria. Bacteria are the most common cause of laboratory-acquired infections due to their ability to survive and multiply in various environments. They can easily contaminate lab equipment and surfaces, leading to infections if proper precautions are not taken. Viruses (choice B) are less common in laboratory-acquired infections as they require specific conditions to survive outside a host. Protozoans (choice C) are larger and less likely to be transmitted in a laboratory setting. Prions (choice D) are misfolded proteins and are not considered living organisms, making them an unlikely source of laboratory infections.
Question 5 of 5
The fluidlike portion of a cell is referred to as:
Correct Answer: C
Rationale: The correct answer is C: cytoplasmic membrane. The cytoplasmic membrane is the fluidlike portion of a cell that separates the cell's contents from the external environment. It regulates the passage of substances in and out of the cell, maintains cell shape, and provides protection. Rationale: 1. Cytosol (choice A) is the liquid component of the cytoplasm where organelles are suspended, not the fluidlike portion of the cell. 2. Nucleoplasm (choice B) refers to the liquid component of the nucleus, not the entire cell. 3. Inclusion (choice D) refers to non-living substances within the cell that are not considered the fluidlike portion. Summary: The cytoplasmic membrane is the correct answer as it encompasses the entire cell and is responsible for maintaining cell integrity and regulating transport. Choices A, B, and D are incorrect as they do not represent the fluidlike portion of the cell.
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