Microbiology Basic and Clinical Principles Test Bank

Correct Answer: A

Rationale: The correct answer is A: Amikacin sulfate. Pseudomonas aeruginosa is commonly resistant to many antibiotics, but aminoglycosides like Amikacin have good activity against it. Step 1: Identify the pathogen causing the infection. Step 2: Consider the antibiotic's spectrum of activity against the pathogen. Step 3: Choose an antibiotic with proven efficacy. Amikacin is a good choice due to its effectiveness against Pseudomonas. Choice B, Benzylpenicillin, is a penicillin which is not effective against Pseudomonas. Choice C, Cephazolin, is a cephalosporin with limited activity against Pseudomonas. Choice D, Erythromycin, is a macrolide which is not effective against Pseudomonas.

Correct Answer: D

Rationale: The correct answer is D because bacteremia can be caused by a variety of bacteria including S.epidermidis, E.coli, S.aureus, P.aeruginosa, K.pneumoniae, and resident skin diphtheroids. Bacteremia refers to the presence of bacteria in the bloodstream, which can occur due to infections from various sources. Choices A and B include common bacteria known to cause bacteremia, while choice C refers to resident skin diphtheroids that can also enter the bloodstream under certain conditions. Therefore, the correct answer is D as it encompasses all the possible etiological causes of bacteremia.

Correct Answer: D

Rationale: The correct answer is D because all of the mentioned bacteria (Escherichia coli, Salmonella enterica, and Pseudomonas aeruginosa) are gram-negative bacteria that produce endotoxins in their cell walls. Endotoxins are released when the bacteria are destroyed, leading to the activation of the immune system and potentially causing septic shock. Escherichia coli and Salmonella enterica are common causes of gastrointestinal infections, while Pseudomonas aeruginosa is known for causing infections in immunocompromised individuals. Therefore, all three bacteria can produce endotoxins that contribute to septic shock. Choices A, B, and C are incorrect because each of these bacteria individually can produce endotoxins that lead to septic shock.

Correct Answer: D

Rationale: The correct answer is D: Lassa virus. The rationale is as follows: 1. Lassa virus belongs to the family Arenaviridae, known for causing Lassa fever. 2. Rabies virus belongs to the Rhabdoviridae family. 3. Crimean-Congo hemorrhagic fever virus belongs to the Nairoviridae family. 4. Epstein-Barr virus belongs to the Herpesviridae family. In summary, Lassa virus is the correct answer because it is the only virus listed that belongs to the Arenaviridae family.

Correct Answer: B

Rationale: The correct answer is B: Malarial plasmodiums. The description of crescent bodies with a pointed end, blue cytoplasm, and red nucleus corresponds to the characteristics of Plasmodium species seen in Romanovsky's stain. Plasmodium species are known to cause malaria and have distinct features like the ones described. Incorrect choices: A: Toxoplasmas - Toxoplasma gondii typically appear as tachyzoites or bradyzoites under staining, not crescent bodies. C: Dermotropic leishmania - Leishmania species appear as amastigotes in tissue smears, not crescent bodies. D: Viscerotropic leishmania - Similar to choice C, Leishmania species do not typically present as crescent bodies in stained specimens.