ATI Pharmacology Quizlet

Correct Answer: B

Rationale: Diazepam, a CNS depressant, can interact with Fentanyl causing severe sedation when administered concurrently. This is due to the additive central nervous system depressant effects of both medications, which can lead to excessive sedation, respiratory depression, and other serious adverse effects. Therefore, healthcare professionals need to monitor clients closely for signs of excessive sedation or respiratory depression when administering these medications together.

Correct Answer: B

Rationale: Isosorbide is an organic nitrate used to manage angina. Concurrent use of sildenafil with organic nitrates, like isosorbide, is contraindicated due to the risk of fatal hypotension. It is essential for clients to avoid taking nitrate medications within 24 hours of using isosorbide to prevent serious complications.

Correct Answer: A

Rationale: When a client is prescribed Prednisone, it is important to increase the intake of vitamin D to help mitigate the risk of bone loss associated with the medication. Vitamin D aids in calcium absorption, supporting bone health in individuals taking Prednisone.

Correct Answer: B

Rationale: Creatine kinase should be monitored in clients taking Atorvastatin as it can indicate muscle damage, a serious adverse effect of statins. Elevated creatine kinase levels may suggest myopathy or rhabdomyolysis, which are potential complications of statin therapy.

Correct Answer: A

Rationale: The nurse should instruct the client to take these medications with food to reduce GI disturbances.