Microbiology Test Bank

Correct Answer: A

Rationale: The correct answer is A: Helicobacter pylori. This bacterium is a major cause of gastric ulcers by disrupting the balance between aggressive (acid, pepsin) and defensive (mucus, bicarbonate, prostaglandins) factors in the stomach lining. H. pylori infection leads to inflammation, weakening the protective mucosal barrier, making the stomach more susceptible to damage. Choices B, C, and D are defensive factors that help protect the stomach lining and prevent ulcer formation, so they do not contribute to the development of gastric ulcers.

Correct Answer: A

Rationale: The correct answer is A: Treponema pallidum. This is because Treponema pallidum is a thin spiral bacteria with 12-14 coils and pointed ends, which matches the description given in the question. Treponema pallidum is the causative agent of syphilis. Choices B, C, and D are incorrect: B: Leptospira - Leptospira is a spiral-shaped bacteria, but it does not have the specific characteristics mentioned in the question. C: Borrelia - Borrelia is another spiral-shaped bacteria, but it does not match the specific features described in the question. D: Spirochaeta - Spirochaeta is a genus of spiral-shaped bacteria, but it does not fit the description of having 12-14 coils and pointed ends as mentioned in the question.

Correct Answer: D

Rationale: The correct answer is D: Single stranded segmented (-) RNA. Orthomyxoviridae family includes influenza viruses, which have a genome composed of single-stranded segmented negative-sense RNA. This specific structure allows for efficient replication and transcription within host cells. Choice A is incorrect as orthomyxoviruses do not have a double-stranded DNA genome. Choice B is incorrect because orthomyxoviruses have a negative-sense RNA genome, not a positive-sense RNA genome. Choice C is incorrect as orthomyxoviruses do not have a double-stranded RNA genome.

Correct Answer: A

Rationale: Step-by-step rationale: 1. Purple-stained diplococci suggest Gram-positive cocci. 2. Capsule presence is a characteristic of Streptococcus pneumoniae. 3. S. pneumoniae is known to form diplococci arrangements. 4. Therefore, the microorganism most likely present is Streptococcus pneumoniae. Summary: - B: Klebsiella pneumoniae is a Gram-negative rod, not a cocci. - C: Neisseria meningitidis is a Gram-negative diplococcus, not a capsule producer. - D: Escherichia coli is a Gram-negative rod, not a cocci or capsule producer.

Correct Answer: D

Rationale: The correct answer is D: Gram-negative bacteria without peptidoglycan. Chlamydia is an intracellular, gram-negative bacteria that lacks peptidoglycan in its cell wall. Peptidoglycan is a key component of the cell wall in most bacteria, but Chlamydia has a unique structure without it. This makes it different from choices A, B, and C, which describe characteristics not applicable to Chlamydia. Choice A is incorrect because Chlamydia is not a gram-positive coccobacteria. Choice B is incorrect because Chlamydia does have a cell wall, albeit lacking peptidoglycan. Choice C is incorrect because Chlamydia is not a gram-negative bacteria with little peptidoglycan, but rather without it.