Pharmacology HESI 2023

Correct Answer: C

Rationale: The correct instruction for a client prescribed methotrexate is to avoid sunlight while taking this medication. Methotrexate can increase sensitivity to sunlight, leading to skin reactions, so clients should limit sun exposure and use protective measures like sunscreen and clothing coverage to prevent adverse effects.

Correct Answer: A

Rationale: The correct instruction for a client taking levodopa-carbidopa for Parkinson's disease is to increase fluid intake to prevent dehydration. Levodopa-carbidopa should be taken with food to reduce gastrointestinal upset and improve absorption. Taking medication at bedtime is not necessary to avoid daytime drowsiness, and it is essential to prevent dehydration due to the medication's side effects.

Correct Answer: A

Rationale: Nitroglycerin sublingual tablets are sensitive to heat and moisture, so they should be stored in a cool, dry place to maintain their efficacy. Choice B is incorrect because nitroglycerin tablets should be taken as directed by the healthcare provider. Choice C is incorrect because sublingual tablets should be placed under the tongue to dissolve, not swallowed. Choice D is incorrect because sublingual tablets should not be chewed; they are meant to be absorbed through the tissues under the tongue.

Correct Answer: B

Rationale: Carbidopa-levodopa increases the amount of levodopa to the CNS, providing more dopamine to the brain. Increased dopamine levels help alleviate Parkinson's symptoms such as tremors, involuntary movements, and gait abnormalities.

Correct Answer: A

Rationale: Corrected Question: When a client with a history of deep vein thrombosis is prescribed fondaparinux, the nurse should monitor for the potential adverse effect of an increased risk of bleeding. Fondaparinux is an anticoagulant that works by preventing blood clots, which can lead to an increased risk of bleeding. Therefore, the nurse should closely monitor the client for signs of bleeding, such as unexplained bruising, bleeding gums, or blood in the urine or stool.